SGSM2 and RAB2A

Data Source:
BioGRID (two hybrid)

		SGSM2	RAB2A
Description		small G protein signaling modulator 2	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Melanosome	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	GTPase Activator Activity Small GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Intracellular Protein Transport Late Endosome To Golgi Transport Positive Regulation Of GTPase Activity Activation Of GTPase Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Post-translational Protein Modification
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fasting blood proinsulin levels ( 23263489) Household income (MTAG) ( 31844048) Insulin-related traits (multivariate analysis) ( 32002517) Multiple sclerosis ( 31604244) Number of sexual partners ( 30643258) Proinsulin levels ( 21873549) Schizophrenia ( 25056061)	Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		20 interacting genes: AFP CA12 CELSR3 CHD3 EGFR FNBP1L GDPD2 ILF2 KHDRBS3 MPP1 MTDH PNO1 PTN RAB2A RAB2B RAB3A RAB3B RAB9B RGMA RPS25	27 interacting genes: BLZF1 CBFB CCDC125 CFL2 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		9905	5862
HPRD ID		15284	01539
Ensembl ID		ENSG00000141258	ENSG00000104388
Uniprot IDs		B9A6J3 O43147	A0A024R7V6 P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?
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