ZBTB24 and CDA

Data Source:
BioGRID (two hybrid)

		ZBTB24	CDA
Description		zinc finger and BTB domain containing 24	cytidine deaminase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Pyrimidine Nucleoside Salvage Neutrophil Degranulation Negative Regulation Of Nucleotide Metabolic Process
Pathways			Neutrophil degranulation Pyrimidine salvage
Drugs			1-Beta-Ribofuranosyl-1,3-Diazepinone Cedazuridine
Diseases
GWAS		Depression in smokers ( 30219690) Height ( 20881960 18391951)	Apolipoprotein A1 levels ( 32203549) Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		70 interacting genes: BACH2 BAX BCL11A BLZF1 C4orf45 CALM1 CCDC136 CCNDBP1 CDA CEP70 CEP76 DDHD1 DNM1L DVL3 FCHO1 GMCL1 GOLGA6L9 HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-2 KRTAP5-9 LDOC1 LHX8 LNX1 LRRC18 MCIDAS MDFI MID2 PDE4DIP PHC2 PICK1 POGZ POU6F2 PRMT7 RALY RBM10 RIN3 SSX2IP SUV39H1 TLE5 TMEM121 TRAF2 TRIM37 TRIM41 TSC22D4 TSGA10 TSPYL2 ZBTB43 ZBTB8A ZBTB9 ZMYM6 ZNF526 ZNF639 ZNF71 ZNF79 ZNF792 ZNF837 ZRANB1	18 interacting genes: ADAT3 ARRDC3 DDIT4L FNDC11 FOXN1 GORASP2 INCA1 KPNA2 KRTAP6-1 KRTAP8-1 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598
Entrez ID		9841	978
HPRD ID		18315	11744
Ensembl ID		ENSG00000112365	ENSG00000158825
Uniprot IDs		O43167	P32320
PDB IDs			1MQ0
Enriched GO Terms of Interacting Partners?
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