SPATA2 and DUT

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SPATA2	DUT
Description		spermatogenesis associated 2	deoxyuridine triphosphatase
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding Receptor Inhibitor Activity Pyrimidine Deoxyribonucleotide Binding Identical Protein Binding Peroxisome Proliferator Activated Receptor Binding
	Biological Process	Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination	Liver Development Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DNA Replication Response To Organic Cyclic Compound Nucleobase-containing Small Molecule Interconversion Regulation Of Protein-containing Complex Assembly DUTP Catabolic Process Negative Regulation Of Signaling Receptor Activity
Pathways
Drugs			Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 20953189 25574825 18364390)	Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)
Interacting Genes		22 interacting genes: ANKRD11 APP ATP6V1H C2CD6 CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 RNF31 TBC1D22B TNIP1 TRAF2 TRIM27 ZNF835	9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2
Entrez ID		9825	1854
HPRD ID		09636	03165
Ensembl ID		ENSG00000158480	ENSG00000128951
Uniprot IDs		A8K0S9 B4DID4 Q9UM82	A0A0C4DGL3 H0YNW5 P33316
PDB IDs		5LJM 5LJN	1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J
Enriched GO Terms of Interacting Partners?
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