CUL7 and PLXNB3

Data Source:
HPRD (two hybrid)

		CUL7	PLXNB3
Description		cullin 7	plexin B3
Image			No pdb structure
GO Annotations	Cellular Component	Anaphase-promoting Complex Cytoplasm Golgi Apparatus Centrosome Cytosol Cullin-RING Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm 3M Complex	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Semaphorin Receptor Activity Protein Domain Specific Binding Rho GDP-dissociation Inhibitor Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cytokinesis Vasculogenesis Epithelial To Mesenchymal Transition Placenta Development Proteolysis Ubiquitin-dependent Protein Catabolic Process Golgi Organization Regulation Of Mitotic Nuclear Division Viral Process Protein Ubiquitination IRE1-mediated Unfolded Protein Response Post-translational Protein Modification Positive Regulation Of Dendrite Morphogenesis	Positive Regulation Of Endothelial Cell Proliferation Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Negative Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Negative Regulation Of Cell Migration Negative Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Positive Chemotaxis Cell Chemotaxis Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways		XBP1(S) activates chaperone genes Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Other semaphorin interactions
Drugs
Diseases		3M syndrome
GWAS
Interacting Genes		9 interacting genes: COMMD1 FBXW8 MEGF10 MTDH MTNR1A PLXNB3 RBX1 SKP1 UBE2M	8 interacting genes: ARHGEF11 BTBD3 CUL7 CUL9 MAGI2 MAGI3 RIT2 SPOCK2
Entrez ID		9820	5365
HPRD ID		09901	02198
Ensembl ID		ENSG00000044090	ENSG00000198753
Uniprot IDs		Q14999	A8K920 Q9ULL4
PDB IDs		2JNG
Enriched GO Terms of Interacting Partners?
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