TSC22D2 and OSBPL1A

Data Source:
BioGRID (two hybrid)

		TSC22D2	OSBPL1A
Description		TSC22 domain family member 2	oxysterol binding protein like 1A
Image		No pdb structure
GO Annotations	Cellular Component		Endosome Late Endosome Cytosol Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Extracellular Exosome
	Molecular Function		Protein Binding Phospholipid Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress	Bile Acid Biosynthetic Process Cholesterol Metabolic Process Sterol Transport Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			Synthesis of bile acids and bile salts MHC class II antigen presentation
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Apolipoprotein A1 levels ( 32203549) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 29891935) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) PR interval ( 32439900) Pulse pressure ( 27841878) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32203549 32154731) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Neutrophil count ( 32888494) Osteoporosis-related phenotypes ( 20548944) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 25483131) White blood cell count ( 32888494)
Interacting Genes		42 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 DNAAF11 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL MED13 MPDZ MSH3 MTIF2 NGRN OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251	5 interacting genes: BAALC MEOX2 PEA15 TIAM1 TSC22D2
Entrez ID		9819	114876
HPRD ID		11101	09472
Ensembl ID		ENSG00000196428	ENSG00000141447
Uniprot IDs		B4DN36 O75157	B0YJ56 B3KU11 Q6GSK5 Q9BXW6
PDB IDs			5ZM5 5ZM6 5ZM7 6IYB
Enriched GO Terms of Interacting Partners?
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