EMC2 and CCDC33

Data Source:
BioGRID (two hybrid)

		EMC2	CCDC33
Description		ER membrane protein complex subunit 2	coiled-coil domain containing 33
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane EMC Complex	Peroxisome
	Molecular Function	Protein Binding Membrane Insertase Activity	Protein Binding
	Biological Process	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Male-pattern baldness ( 27182965 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)	Bacterial meningitis ( 31092817) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Obesity-related traits ( 23251661) Systolic blood pressure ( 30578418)
Interacting Genes		8 interacting genes: CCDC33 EMC8 EMC9 IKZF3 PCDHB12 RHOU SH3BP5L SS18L2	159 interacting genes: ABCF3 ABLIM3 ANKS1A AP1M1 APP ARHGEF6 ARIH2 ARMC7 ARNT2 BCCIP BLK BLZF1 BYSL C1orf109 CABP2 CALCOCO2 CCDC102B CCDC57 CCDC6 CCDC85B CCHCR1 CCNH CDC23 CDCA7L CDKN2B CENPP CFAP206 CHCHD3 CINP CIR1 CRYBA2 CRYBA4 CTNNA3 DGCR6 DIP2A DVL2 DVL3 EAF1 EFEMP2 EHMT2 EMC2 EMD ESRRG EXOC8 FAM124A FAM161A FAM214B FRS3 FXR2 GCC1 GPANK1 GPATCH2L GRN GYS1 HEXIM2 HGS HNRNPF HNRNPK HOOK2 HOXA1 HSF2BP IL16 ING5 ITGB1BP1 KANK2 KCTD19 KCTD9 KDM1A KHDRBS3 KIFC3 KLHL38 KXD1 L3MBTL2 LDOC1 LMO1 LMO2 LMO3 LNX1 MAGED1 MAGOHB MAPK9 MDFI MFAP1 MID2 MIPOL1 MISP MKRN3 MLH1 MOS NAB2 NCK2 NDOR1 NECAB2 NEFL NINL NME7 OSGIN1 OSTF1 PCSK5 PID1 PIK3R3 PIN1 PLA2G6 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAA2 PRKAB2 PRPF31 PTGER3 PTK6 QARS1 RAD51D RAD54B RBMX RHOXF2 RNF6 SCNM1 SMAD3 SMARCB1 SMARCD1 SMYD1 SPAG5 SPG21 STK16 STX11 SYT17 TASOR2 TCEANC TGFB1 TMCC2 TNS2 TRAF2 TRIM23 TRIM37 TRIM42 TRIM59 TSC22D4 TSEN15 TSGA10 TTC19 TUFT1 TXK TXLNA UBASH3A UBQLN4 USHBP1 VPS52 WT1 YES1 ZBTB8A ZGPAT ZNF330 ZNF572 ZNF688 ZNF76 ZNRD2
Entrez ID		9694	80125
HPRD ID		09657	09959
Ensembl ID		ENSG00000104412	ENSG00000140481
Uniprot IDs		Q15006	Q8N5R6
PDB IDs		6WW7 6Y4L 6Z3W
Enriched GO Terms of Interacting Partners?
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