PPM1F and FEM1A

Data Source:
HPRD (in vivo)

		PPM1F	FEM1A
Description		protein phosphatase, Mg2+/Mn2+ dependent 1F	fem-1 homolog A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Ubiquitin Ligase Complex Cytosol
	Molecular Function	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding EP4 Subtype Prostaglandin E2 Receptor Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Protein Dephosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Positive Regulation Of Cell Migration Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Negative Regulation Of Protein Transport Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Peptidyl-serine Dephosphorylation Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Localization Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification Negative Regulation Of Inflammatory Response Regulation Of Ubiquitin-protein Transferase Activity
Pathways		Negative regulation of NMDA receptor-mediated neuronal transmission	Neddylation
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder ( 31043756)	Height ( 31562340)
Interacting Genes		19 interacting genes: AATK ARHGEF7 CAMK2A ERBB2 ERBB3 ERBB4 FAM161A FEM1A FEM1B KLHL8 LATS1 LMTK2 MARS1 MEOX1 PAK1 PRKAA1 PTK7 ROR1 ROR2	11 interacting genes: ACAA1 GOLGA6L9 INCA1 KIFC3 MALT1 MYOM3 NDUFAB1 OGFOD1 PPM1F PTGER4 WWOX
Entrez ID		9647	55527
HPRD ID		10163	16888
Ensembl ID		ENSG00000100034	ENSG00000141965
Uniprot IDs		B5MCT7 P49593	Q9BSK4
PDB IDs
Enriched GO Terms of Interacting Partners?
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