SEC24C and MOS

Data Source:
BioGRID (two hybrid)

		SEC24C	MOS
Description		SEC24 homolog C, COPII coat complex component	MOS proto-oncogene, serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Cytoplasm Cytosol
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating COPII-coated Vesicle Cargo Loading	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Meiotic Spindle Organization Chromatin Organization Signal Transduction Regulation Of Meiotic Nuclear Division Positive Regulation Of MAPK Cascade Protein Autophosphorylation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)	Height ( 18391951) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	56 interacting genes: ACTN2 ASB6 ATRIP BICD2 BMPR2 BORCS6 CALCOCO2 CBY2 CCDC102B CCDC136 CCDC33 CCNDBP1 DYDC1 DZIP1 GFAP GOLGA2 GOLGA6A GOLGA6L9 GRAP2 HOMER3 HOMEZ HSPA1A IKZF1 KCTD6 KIFAP3 KIFC3 KRT13 KRT15 KRT27 KRT31 KRT33B KRT34 KRT40 KRTAP1-3 LZTS2 MAP2K2 MEOX2 MID2 MIPOL1 MTMR9 MTUS2 MYOD1 NBPF19 NOTCH2NLA PICK1 PPP2R5A PSTPIP1 RHOU SEC24C SSX2IP TP53BP2 TRAF1 TRAF2 TRIM27 USHBP1 ZBTB2
Entrez ID		9632	4342
HPRD ID		06217	01816
Ensembl ID		ENSG00000176986	ENSG00000172680
Uniprot IDs		A0A024QZM6 P53992	P00540
PDB IDs		3EH2
Enriched GO Terms of Interacting Partners?
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