GNA14 and DNAL4

Data Source:
BioGRID (two hybrid)

		GNA14	DNAL4
Description		G protein subunit alpha 14	dynein axonemal light chain 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Extracellular Exosome	Cytoplasm Microtubule Plasma Membrane Cilium Dynein Complex
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding Type 2A Serotonin Receptor Binding Metal Ion Binding	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Action Potential Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Platelet Activation Phospholipase C-activating Dopamine Receptor Signaling Pathway	Microtubule-based Movement Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed
Pathways		Acetylcholine regulates insulin secretion Acetylcholine regulates insulin secretion G alpha (q) signalling events G alpha (q) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 Thromboxane signalling through TP receptor Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Thrombin signalling through proteinase activated receptors (PARs)	Retrograde neurotrophin signalling
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Bipolar disorder ( 31043756) Delirium ( 29631748) Thoracic aortic calcification levels ( 31659325)
Interacting Genes		9 interacting genes: ADRB2 CCR1 CHRM2 CXCR1 CXCR2 DNAL4 JMJD6 OPRL1 SSTR2	16 interacting genes: CAMK2D CHIC2 DYNLL1 DYNLL2 FHL5 GNA14 GPBP1 KRTAP10-3 KRTAP12-3 KRTAP9-8 NFATC2IP NOTCH2NLA NTAQ1 NUDT22 SCTR TRIM54
Entrez ID		9630	10126
HPRD ID		05095	13239
Ensembl ID		ENSG00000156049	ENSG00000100246
Uniprot IDs		O95837	O96015
PDB IDs
Enriched GO Terms of Interacting Partners?
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