CD48 and P4HA1

Data Source:
BioGRID (biochemical)

		CD48	P4HA1
Description		CD48 molecule	prolyl 4-hydroxylase subunit alpha 1
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Antigen Binding Protein Binding Signaling Receptor Activity	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding Identical Protein Binding
	Biological Process	Regulation Of Adaptive Immune Response Defense Response Leukocyte Migration	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways		Cell surface interactions at the vascular wall	Collagen biosynthesis and modifying enzymes
Drugs			Ascorbic acid Proline Hydralazine
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		10 interacting genes: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK	2 interacting genes: MLF2 SUMO2
Entrez ID		962	5033
HPRD ID		00177	08901
Ensembl ID		ENSG00000117091	ENSG00000122884
Uniprot IDs		A0A087X1S7 P09326	P13674 Q5VSQ6
PDB IDs		2EDO	1TJC 2V5F 2YQ8 4BT8 4BT9 4BTA 4BTB
Enriched GO Terms of Interacting Partners?
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