RAB3D and AP1M2

Data Source:
BioGRID (two hybrid)

		RAB3D	AP1M2
Description		RAB3D, member RAS oncogene family	adaptor related protein complex 1 subunit mu 2
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding	Protein Binding Clathrin Adaptor Activity
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway	Protein Targeting Vesicle Targeting Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		Neutrophil degranulation RAB geranylgeranylation	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)	Bipolar disorder ( 31043756) Lymphocyte percentage of white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		15 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF RIMS2 RNF32 RPH3AL SYTL4 VRTN	20 interacting genes: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		9545	10053
HPRD ID		05070	06296
Ensembl ID		ENSG00000105514	ENSG00000129354
Uniprot IDs		A0A024R7G2 O95716	Q53GI5 Q9Y6Q5
PDB IDs		2GF9
Enriched GO Terms of Interacting Partners?
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