BAG5 and SIVA1

Data Source:
BioGRID (genetic interference)

		BAG5	SIVA1
Description		BAG cochaperone 5	SIVA1 apoptosis inducing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway
Pathways		Regulation of HSF1-mediated heat shock response
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)	Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		19 interacting genes: BANP CDCA7L CIRBP DES EFEMP1 FAM118B GOLGA6A HSPA4 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SNCA STUB1 THAP1 TP53 TRIM27	30 interacting genes: ABL2 APP AQP1 BCL2L1 BEX3 C2orf68 CATSPER1 CD27 CD4 CDKN2A CREB5 HOXA1 ING3 KRTAP26-1 MEFV NEDD4 NEDD4L NTAQ1 PCNA PM20D2 POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TFAP2D TNFRSF4 UBE2D1 ZNF446
Entrez ID		9529	10572
HPRD ID		04862	16124
Ensembl ID		ENSG00000166170	ENSG00000184990
Uniprot IDs		A0A024R6M6 Q9UL15	O15304
PDB IDs		2D9D 3A8Y
Enriched GO Terms of Interacting Partners?
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