SIVA1 and TNFRSF4

Data Source:
HPRD (in vitro)

		SIVA1	TNFRSF4
Description		SIVA1 apoptosis inducing factor	TNF receptor superfamily member 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	Virus Receptor Activity Tumor Necrosis Factor Receptor Binding CD27 Receptor Binding Protein Binding Metal Ion Binding	Virus Receptor Activity Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Viral Entry Into Host Cell Extrinsic Apoptotic Signaling Pathway	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Positive Regulation Of B Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway T Cell Proliferation Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell
Pathways			TNFs bind their physiological receptors
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Endometrial cancer ( 27135401) Endometrial endometrioid carcinoma ( 27135401) Thyroid stimulating hormone levels ( 32769997)	Inflammatory bowel disease ( 23128233)
Interacting Genes		30 interacting genes: ABL2 APP AQP1 BCL2L1 BEX3 C2orf68 CATSPER1 CD27 CD4 CDKN2A CREB5 HOXA1 ING3 KRTAP26-1 MEFV NEDD4 NEDD4L NTAQ1 PCNA PM20D2 POLR2M PXMP2 RAD18 RHOU SSBP3 TCAP TFAP2D TNFRSF4 UBE2D1 ZNF446	10 interacting genes: NUFIP2 RC3H1 SIVA1 TNFRSF9 TNFSF4 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5
Entrez ID		10572	7293
HPRD ID		16124	02636
Ensembl ID		ENSG00000184990	ENSG00000186827
Uniprot IDs		O15304	P43489
PDB IDs			1D0A 2HEV 2HEY 6OGX 6OKM 6OKN
Enriched GO Terms of Interacting Partners?
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