VPS4B and KATNAL1

Data Source:
BioGRID (two hybrid)

		VPS4B	KATNAL1
Description		vacuolar protein sorting 4 homolog B	katanin catalytic subunit A1 like 1
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GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Endosome Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Exosome Flemming Body	Spindle Pole Nucleus Cytoplasm Centrosome Spindle Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding	Protein Binding ATP Binding Microtubule Binding Microtubule-severing ATPase Activity Isomerase Activity ATPase Activity Identical Protein Binding
	Biological Process	Potassium Ion Transport Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Viral Release From Host Cell Cholesterol Transport Cytoplasmic Microtubule Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Viral Process Regulation Of Viral Process Microtubule Severing Protein Depolymerization Negative Regulation Of Cell Death Late Endosomal Microautophagy Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Life Cycle ESCRT III Complex Disassembly	Spermatogenesis Cytoplasmic Microtubule Organization Microtubule Severing
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Pyoderma gangrenosum in inflammatory bowel disease ( 24487271)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Blood osmolality (transformed sodium) ( 28360221) Fat distribution (HIV) ( 21897333) Male-pattern baldness ( 27182965) Refractive error ( 32231278) Type 2 diabetes ( 31049640)
Interacting Genes		8 interacting genes: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 KATNAL1 VPS4A ZFYVE19	17 interacting genes: ASCC2 BYSL C1orf109 CEP57L1 COX17 CTNNA3 GCC1 GUCA1A IQUB KATNBL1 KLC4 MEOX2 PGAM2 PITPNC1 SIAH1 VPS4B ZNF69
Entrez ID		9525	84056
HPRD ID		15653	13753
Ensembl ID		ENSG00000119541	ENSG00000102781
Uniprot IDs		A0A024R2C5 O75351	A0A024RDP8 B3KUK7 Q9BW62
PDB IDs		1WR0 1XWI 2CPT 2JQH 2JQK 4U7Y	6B5C
Enriched GO Terms of Interacting Partners?
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