AKAP6 and PABPN1

Data Source:
BioGRID (affinity chromatography technology)

		AKAP6	PABPN1
Description		A-kinase anchoring protein 6	poly(A) binding protein nuclear 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Caveola Junctional Sarcoplasmic Reticulum Membrane Intercalated Disc Sarcoplasmic Reticulum T-tubule Nuclear Membrane Calcium Channel Complex Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex
	Molecular Function	Protein Binding Adenylate Cyclase Binding Protein Kinase A Regulatory Subunit Binding Protein-membrane Adaptor Activity Ion Channel Binding Protein Kinase A Binding Molecular Adaptor Activity	RNA Binding Protein Binding RNA Polymerase Binding
	Biological Process	Action Potential Protein Targeting Regulation Of Protein Kinase A Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum CAMP-mediated Signaling Positive Regulation Of Cell Growth Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Membrane Repolarization Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To CAMP Cellular Response To Cytokine Stimulus Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Delayed Rectifier Potassium Channel Activity	MAPK Cascade MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity
Pathways			Inhibition of Host mRNA Processing and RNA Silencing mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases			Oculopharyngeal muscular dystrophy (OPMD)
GWAS		Adult body size ( 32376654) Anorexia nervosa ( 21079607) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 29273806) Atrial fibrillation ( 30061737 29892015) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Coffee consumption ( 31046077) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 25644384) Creatine kinase levels ( 29403010) Diisocyanate-induced asthma ( 25918132) Economic and political preferences (environmentalism) ( 22566634) Fasting blood insulin (BMI interaction) ( 22581228) General cognitive ability ( 29844566) Glioma ( 28346443) HDL cholesterol levels ( 32203549) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Non-glioblastoma glioma ( 28346443) Photic sneeze reflex ( 27182965) PR interval ( 32439900) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Type 2 diabetes ( 30297969)	Body mass index ( 26865924) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		9 interacting genes: CALM1 CDC5L DISC1 DTNBP1 PDE4D PPP2CA PRKAR2A RYR1 RYR2	13 interacting genes: CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ
Entrez ID		9472	8106
HPRD ID		05257	03787
Ensembl ID		ENSG00000151320	ENSG00000100836
Uniprot IDs		B2RP22 Q13023	Q86U42
PDB IDs			3B4D 3B4M 3UCG
Enriched GO Terms of Interacting Partners?
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