IL27RA and GALNT15

Data Source:
BioGRID (two hybrid)

		IL27RA	GALNT15
Description		interleukin 27 receptor subunit alpha	polypeptide N-acetylgalactosaminyltransferase 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Interleukin-12 Receptor Complex Receptor Complex Interleukin-23 Receptor Complex	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Transport Vesicle
	Molecular Function	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity Interleukin-12 Receptor Binding Protein Binding Cytokine Binding Interleukin-23 Binding Interleukin-27 Receptor Activity	Polypeptide N-acetylgalactosaminyltransferase Activity Protein Binding Carbohydrate Binding Metal Ion Binding
	Biological Process	Positive Regulation Of T-helper 1 Type Immune Response Negative Regulation Of Type 2 Immune Response Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interferon-gamma Production Positive Regulation Of Activated T Cell Proliferation Regulation Of Isotype Switching To IgG Isotypes Defense Response To Gram-positive Bacterium Interleukin-27-mediated Signaling Pathway Interleukin-35-mediated Signaling Pathway Negative Regulation Of T-helper 17 Type Immune Response Negative Regulation Of T Cell Extravasation	O-glycan Processing Protein Phosphopantetheinylation
Pathways		Interleukin-35 Signalling Interleukin-27 signaling Interleukin-27 signaling	O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Immune response to measles-mumps-rubella vaccine ( 24811271) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494)	Numerical cognitive ability ( 31620175) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		12 interacting genes: BRICD5 CLDN2 DEFB121 DERL3 EBI3 GALNT15 IL27 MAPK8 MFSD5 SLC41A2 STAT1 YIPF6	18 interacting genes: CD200R1 CD79A CISD2 EVI2B FCRL6 FFAR2 FNDC9 GOLM1 IL27RA MR1 MUC1 PDCD1LG2 PDZK1IP1 SLC30A2 SLC7A1 SPSB2 SYNPR TMEM179B
Entrez ID		9466	117248
HPRD ID		09247	13563
Ensembl ID		ENSG00000104998	ENSG00000131386
Uniprot IDs		Q6UWB1	B3KT16 C9JGI4 Q4G146 Q8N3T1
PDB IDs
Enriched GO Terms of Interacting Partners?
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