HOMER3 and FRYL

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		HOMER3	FRYL
Description		homer scaffold protein 3	FRY like transcription coactivator
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite	Cell Cortex Site Of Polarized Growth
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Protein Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Cell Morphogenesis Neuron Projection Development
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Height ( 31562340) Hemoglobin ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 29403010) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		86 interacting genes: ABI1 ABI2 ABI3 APP ARL13B C1orf116 C4orf17 CCDC120 CCDC141 CCDC187 CDC37 CDK18 CEBPB CWF19L2 DVL3 DYNLL1 DYNLL2 EAF1 EFHC1 EIF3D FAM161B FAM90A1 FAT1 FBXO28 FRYL GAS8 GGN GRM5 HOMER1 HOXB5 INCA1 ITPR1 KANK2 KANK4 KDM1A KRTAP19-7 LHX2 LNX1 LRRC7 LSM14B MDM1 MEOX1 MFAP1 MIA3 MOS MSS51 NEBL NTAQ1 OTX2 PALLD PAX6 PAX7 PKN1 PLAAT5 POLI POM121 PPP1R18 PPP1R32 PRCC PRR35 PSMA1 PSMA2 PSMC5 PSORS1C2 RBM14 RBM22 RUNX1T1 RYR1 SAXO1 SCNM1 SDCBP SLAIN1 SMR3B SNRPF SRPK2 TBC1D22B TOX2 TRPC1 USP2 WBP2 WIPF1 ZBTB4 ZNF19 ZNF35 ZNF414 ZNF655	6 interacting genes: CCDC187 DISC1 HOMER3 PDCD10 PELI2 PRR35
Entrez ID		9454	285527
HPRD ID		07270	18995
Ensembl ID		ENSG00000051128	ENSG00000075539
Uniprot IDs		Q9NSC5	B3KXG5 O94915 Q6ZR29
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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