MED27 and MED22

Data Source:
HPRD (in vitro)

		MED27	MED22
Description		mediator complex subunit 27	mediator complex subunit 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytosol Mediator Complex	Cytoplasm Mediator Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding	Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription By RNA Polymerase II
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Gout (normal type) ( 32238385) Triglyceride levels ( 32203549)	Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058) Malaria ( 31844061)
Interacting Genes		11 interacting genes: AFP ARFGAP1 ESR1 FBXO7 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5	12 interacting genes: FBXO7 GOLM1 HGS MED11 MED17 MED27 MED30 MED8 MED9 NTAQ1 THOC7 TXNDC9
Entrez ID		9442	6837
HPRD ID		05438	01713
Ensembl ID		ENSG00000160563	ENSG00000148297
Uniprot IDs		A0A024R8B7 Q6P2C8	A0A024R8C5 Q15528
PDB IDs
Enriched GO Terms of Interacting Partners?
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