SYTL4 and SPANXN2

Data Source:
BioGRID (two hybrid)

		SYTL4	SPANXN2
Description		synaptotagmin like 4	SPANX family member N2
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle
	Molecular Function	Protein Binding Phospholipid Binding Neurexin Family Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Plasma Membrane Repair Platelet Degranulation Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair
Pathways		Platelet degranulation
Drugs		Insulin pork
Diseases
GWAS		Lean body mass ( 28552196) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		27 interacting genes: CCDC85B CEP70 DVL3 FCHO1 FXR2 HMG20A INS KIFC3 LMO1 LZTS1 OSBPL3 PRKAR1B RAB27A RAB27B RAB3A RAB3D RAB8A ROPN1 SPANXN2 STX1A STXBP1 TBC1D1 TRIM37 TRIM41 ZBTB7B ZBTB9 ZRANB1	51 interacting genes: ANKRD1 ANKRD11 BANP BEND7 BHLHB9 BIVM CAVIN1 CDC14B CDCA8 CDYL2 COIL DPPA4 EPB41L3 FAM193B FAM204A H2BC11 H2BC15 H2BC21 KHDC4 KRCC1 L3MBTL3 MEOX2 MTIF3 NOL12 NUMB PBX4 PICK1 RPL27 RRP1 SFMBT1 SMN1 SMN2 SNIP1 SNRPD2 SP3 SP4 SRP14 STAC3 SYTL4 THAP1 TNNI1 VAX1 YAF2 ZBTB48 ZNF19 ZNF2 ZNF438 ZNF526 ZNF655 ZNF75A ZNF84
Entrez ID		94121	494119
HPRD ID		06735	18091
Ensembl ID		ENSG00000102362	ENSG00000268988
Uniprot IDs		A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24	Q5MJ10
PDB IDs		2CSZ 3FDW 5X6T
Enriched GO Terms of Interacting Partners?
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