ZRANB2 and SNRNP70

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		ZRANB2	SNRNP70
Description		zinc finger RANBP2-type containing 2	small nuclear ribonucleoprotein U1 subunit 70
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GO Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Lipopolysaccharide Binding RNA Binding Protein Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding
	Biological Process	MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Verbal declarative memory ( 25648963)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653)
Interacting Genes		14 interacting genes: AKAP17A CSNK2A1 EP300 KIF20A LRRK2 SMN1 SNRNP70 SREK1 SRPK1 SRPK2 SRSF2 TRA2B U2AF1 YY1	46 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2
Entrez ID		9406	6625
HPRD ID		09185	01617
Ensembl ID		ENSG00000132485	ENSG00000104852
Uniprot IDs		O95218	A0A024QZD5 P08621 Q9UFS1
PDB IDs		1N0Z 2K1P 3G9Y	2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9
Enriched GO Terms of Interacting Partners?
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