LPXN and RNF214

Data Source:
BioGRID (two hybrid)

		LPXN	RNF214
Description		leupaxin	ring finger protein 214
Image			No pdb structure
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coregulator Activity Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Cell Adhesion Negative Regulation Of Cell Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Negative Regulation Of B Cell Receptor Signaling Pathway Protein-containing Complex Assembly	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Lymphoma ( 23349640) Pulse pressure ( 30578418) Ulcerative colitis ( 28067908)	Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) HDL cholesterol levels ( 32203549) Sensorimotor dexterity ( 31596458)
Interacting Genes		33 interacting genes: AGXT AQP1 GIT1 HDAC6 HOXA1 HOXC9 IKBKG IMP3 ITGA4 LIMS1 LMO1 LMO3 MAP2K7 MAPK6 NDN NR3C1 PHF21A PLEKHH2 PLEKHN1 PLSCR4 POM121 PTK2 PTK2B PTPN12 RNF214 RUNX1T1 SFI1 TGFB1 TNS2 TXLNB VCL ZNF175 ZNF426	5 interacting genes: GGA3 GOLGA2 LPXN TRIP6 ZNF76
Entrez ID		9404	257160
HPRD ID		05651	16815
Ensembl ID		ENSG00000110031	ENSG00000167257
Uniprot IDs		B7Z5P7 O60711	A0A024R3D4 Q8ND24
PDB IDs		1X3H 4XEF 4XEK 4XEV
Enriched GO Terms of Interacting Partners?
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