COPB2 and TMED10

Data Source:
BioGRID (pull down)

		COPB2	TMED10
Description		COPI coat complex subunit beta 2	transmembrane p24 trafficking protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol COPI Vesicle Coat Transport Vesicle	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Gamma-secretase Complex
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Protein Transmembrane Transporter Activity Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Toxin Transport	Kidney Development Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Interleukin-1 Production Vesicle Cargo Loading COPI-coated Vesicle Budding Response To Alkaloid Regulated Exocytosis Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Positive Regulation Of Protein Secretion Protein Transmembrane Transport Protein Localization To ERGIC Cytosol To ERGIC Protein Transport Regulation Of Amyloid-beta Formation Negative Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Kawasaki disease ( 22446961) Male-pattern baldness ( 29146897)	Coronary artery disease ( 32469254) Heel bone mineral density ( 30598549) Height ( 19343178) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: ARCN1 COPA COPE MCPH1 MFHAS1 NDRG1 NFKB1 PRKCE RGS2 RGS4 SACM1L SUMO2 TMED10 WBP2	20 interacting genes: APH1A ARCN1 ARF1 CDC42 COPA COPB1 COPB2 COPE COPG1 COPG2 COPZ1 DHODH FBXO7 GORASP2 NCSTN NPSR1 PSENEN SEC23B SLC13A1 TMED2
Entrez ID		9276	10972
HPRD ID		06103	12013
Ensembl ID		ENSG00000184432	ENSG00000170348
Uniprot IDs		P35606	A0A024R6I3 P49755
PDB IDs
Enriched GO Terms of Interacting Partners?
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