FAM114A1 and RAB2A

Data Source:
BioGRID (two hybrid, two hybrid)

		FAM114A1	RAB2A
Description		family with sequence similarity 114 member A1	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Cytosol	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process		Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Post-translational Protein Modification
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS		Alcohol dependence ( 24166409) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Helicobacter pylori serologic status ( 23652523) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643)	Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		9 interacting genes: AGTRAP CMTM5 GDAP1 RAB2A RAB2B SNAPIN SPG21 TNFRSF10D TNS2	27 interacting genes: BLZF1 CBFB CCDC125 CFL2 FAM114A1 FAM114A2 FAM71A FAM71C FAM71F2 FRMD1 GAPDH GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 PMAIP1 PRKCI RBSN RGS2 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		92689	5862
HPRD ID		11282	01539
Ensembl ID		ENSG00000197712	ENSG00000104388
Uniprot IDs		A1MMZ0 Q8IWE2	A0A024R7V6 P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?
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