CYTH1 and INAVA

Data Source:
BioGRID (pull down)

		CYTH1	INAVA
Description		cytohesin 1	innate immunity activator
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Nucleus Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding	Protein Binding
	Biological Process	Vesicle-mediated Transport Regulation Of Cell Adhesion Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity Establishment Of Epithelial Cell Polarity	Activation Of MAPK Activity Pattern Recognition Receptor Signaling Pathway Cytokine Production Involved In Immune Response Positive Regulation Of Protein Ubiquitination Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Stress-activated MAPK Cascade Adherens Junction Maintenance Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Intestinal Epithelial Structure Maintenance Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Reactive Oxygen Species Biosynthetic Process
Pathways		Intra-Golgi traffic
Drugs
Diseases
GWAS		Anxiety and major depressive disorder ( 24047446) Atrial fibrillation ( 30061737) HDL cholesterol levels ( 32203549) Pulse pressure ( 27841878 30578418) Red cell distribution width ( 32888494) Systolic blood pressure ( 27841878)	Celiac disease ( 30572963)
Interacting Genes		16 interacting genes: ACTA1 ARF1 ARF6 ARFRP1 CCDC120 CNKSR1 CYTIP FOSL2 GNAQ INAVA IPCEF1 ITGB2 ITSN1 PRKCD SNAPC5 TRIM23	3 interacting genes: CYTH1 CYTH2 CYTH3
Entrez ID		9267	55765
HPRD ID		01630	07712
Ensembl ID		ENSG00000108669	ENSG00000163362
Uniprot IDs		B7Z9W0 Q15438	Q3KP66
PDB IDs		1BC9 4A4P
Enriched GO Terms of Interacting Partners?
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