TIFA and ARHGEF39

		TIFA	ARHGEF39
Description		TRAF interacting protein with forkhead associated domain	Rho guanine nucleotide exchange factor 39
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Plasma Membrane
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Cytoplasmic Pattern Recognition Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Homooligomerization	Positive Regulation Of Cell Migration Regulation Of Catalytic Activity
Pathways		Alpha-protein kinase 1 signaling pathway	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Body mass index ( 26426971) Rheumatoid arthritis ( 30891314)
Interacting Genes		23 interacting genes: AP1M1 ARHGEF39 DVL2 GSDME IRAK1 KANK2 LNX1 LNX2 NIF3L1 NTAQ1 NUDT18 NXF1 PRKAA2 RIPPLY3 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF1 TRAF2 TRAF6 TXN2	4 interacting genes: CALCOCO2 DVL2 RBPMS TIFA
Entrez ID		92610	84904
HPRD ID		09835	12929
Ensembl ID		ENSG00000145365	ENSG00000137135
Uniprot IDs		Q96CG3	Q8N4T4
PDB IDs		4YM4 4ZGI 5ZUJ 6A33
Enriched GO Terms of Interacting Partners?
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