CD5 and CD79B

Data Source:
HPRD (in vivo)

		CD5	CD79B
Description		CD5 molecule	CD79b molecule
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane B Cell Receptor Complex Extracellular Exosome
	Molecular Function	Scavenger Receptor Activity Protein Binding Signaling Receptor Activity	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Endocytosis Cell Recognition T Cell Costimulation Apoptotic Signaling Pathway	Adaptive Immune Response Immune Response Signal Transduction B Cell Differentiation B Cell Receptor Signaling Pathway
Pathways			CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs			Polatuzumab vedotin
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Coffee consumption ( 31046077) Gut microbiota (bacterial taxa) ( 27694959) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 24076602 21833088) Rheumatoid arthritis ( 30423114 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Height ( 25282103)
Interacting Genes		21 interacting genes: CAMK2D CBL CD2 CD247 CD4 CD6 CD72 CD79A CD79B CSNK2A1 DYNLT3 FYN HNRNPU LCK PIK3R1 PRKCA PRKCB PRKCG PTPN6 RASA1 ZAP70	14 interacting genes: BLK CD19 CD3E CD5 CD79A FYN LCK LYN PTK2 PTPN6 SGTA SGTB SYK ZAP70
Entrez ID		921	974
HPRD ID		01078	00922
Ensembl ID		ENSG00000110448	ENSG00000007312
Uniprot IDs		P06127	P40259
PDB IDs		2JA4 2JOP 2JP0 2OTT	3KG5
Enriched GO Terms of Interacting Partners?
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