TTC5 and JMY

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TTC5	JMY
Description		tetratricopeptide repeat domain 5	junction mediating and regulatory protein, p53 cofactor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Cell Leading Edge
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	Transcription Coactivator Activity Actin Binding Protein Binding Arp2/3 Complex Binding
	Biological Process	DNA Repair Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator	DNA Repair Regulation Of Transcription By RNA Polymerase II Cell Cycle Arrest Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity 'de Novo' Actin Filament Nucleation Actin Polymerization-dependent Cell Motility Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Regulation of TP53 Activity through Methylation	Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282)	Blood and toenail selenium levels ( 25343990) Platelet distribution width ( 32888494) Toenail selenium levels ( 25343990)
Interacting Genes		9 interacting genes: CAMK2A CAMK2B CAMK2D CAMK2G CAVIN1 DDIT4L GOLGA6A HDX JMY	8 interacting genes: CCDC136 EP300 GOLGA6L9 MDM2 MTUS2 RBM48 RINT1 TTC5
Entrez ID		91875	133746
HPRD ID		15584	05045
Ensembl ID		ENSG00000136319	ENSG00000152409
Uniprot IDs		Q86T04 Q8N0Z6	Q8N9B5
PDB IDs		2XVS 6T59
Enriched GO Terms of Interacting Partners?
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