YTHDC1 and CFH

  • Data Source:
  • BioGRID (two hybrid)

YTHDC1

CFH

Description YTH domain containing 1 complement factor H
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 22694956 23326517 23577725 23455636 23536807 20861866 21665990 15761122)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (extreme sampling) ( 23577725)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Age-related macular degeneration (MTAG) ( 32277175)
  • Blood protein levels ( 29875488 28240269)
  • Chronic central serous retinopathy ( 30480742 30073298)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Complement C3 and C4 levels ( 23028341)
  • Complement factor H binding to malondialdehyde ( 32321835)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
  • Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
  • Early age-related macular degeneration ( 32843070)
  • Exudative age-related macular degeneration ( 25629512)
  • Fuchs's corneal dystrophy ( 28358029)
  • Matrix metalloproteinase-8 levels ( 29212897)
  • Meningococcal disease ( 20694013)
  • Neovascular age-related macular degeneration ( 28703135)
  • Nephropathy ( 21399633)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Serum C3d:C3 ratio (systemic complement activation) ( 29398083)
  • Sub-foveal choroidal thickness ( 29844195)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 42 interacting genes: ABL1 ADAMTS4 ANKRD28 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 KRTAP10-6 LAMC3 LAMTOR5 LZTS2 MPRIP PHF19 PICK1 PLG PROSER2 RBMY1A1 RBMY1F RBMY1J RNPS1 SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51 16 interacting genes: ADM C3 CFHR1 CFI CRP DMP1 EP300 GRB2 ITGAM PTX3 SELL SMAD3 THBS1 VDR YTHDC1 ZBTB16
Entrez ID 91746 3075
HPRD ID 11689 00601
Ensembl ID ENSG00000083896 ENSG00000000971
Uniprot IDs J3QR07 Q96MU7 A0A024R962 A0A0D9SG88 P08603
PDB IDs 2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7 6SYZ 6SZ1 6SZ2 6SZ3 6SZL 6SZN 6SZR 6SZT 6SZX 6SZY 6T01 6T02 6T03 6T04 6T05 6T06 6T07 6T08 6T09 6T0A 6T0C 6T0D 6T0O 6T0X 6T0Z 6T10 6T11 6T12 6WE8 6WE9 6WEA 6YKE 6YKI 6YKJ 6YKZ 6YL0 6YL8 6YL9 6YNI 6YNJ 6YNK 6YNL 6YNM 6YNN 6YNO 6YNP 6YOQ 6ZCM 6ZCN 6ZD9 1FHC 1HAQ 1HCC 1HFH 1HFI 1KOV 2BZM 2G7I 2IC4 2JGW 2JGX 2KMS 2QFG 2QFH 2RLP 2RLQ 2UWN 2V8E 2W80 2W81 2WII 2XQW 3GAU 3GAV 3GAW 3KXV 3KZJ 3OXU 3R62 3RJ3 3SW0 4AYD 4AYE 4AYI 4AYM 4B2R 4B2S 4J38 4K12 4ONT 4ZH1 5NBQ 5O32 5O35 5WTB 6ATG
Enriched GO Terms of Interacting Partners?
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