EBAG9 and ORMDL1

Data Source:
BioGRID (two hybrid)

		EBAG9	ORMDL1
Description		estrogen receptor binding site associated antigen 9	ORMDL sphingolipid biosynthesis regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane Secretory Granule	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane SPOTS Complex
	Molecular Function	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process	Protein Binding
	Biological Process	Regulation Of Cell Growth Apoptotic Process	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process
Pathways		Estrogen-dependent gene expression	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)	Bilirubin levels ( 20639394) Ferritin levels ( 25162662)
Interacting Genes		28 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB	37 interacting genes: APP AQP6 ARL13B ASGR2 COQ9 CPLX4 CREB3 CREB3L1 EBAG9 EBP EHHADH ERGIC3 GPR152 HSD17B11 KCNK4 LMNA LNX1 MFSD14B PCNX2 PGRMC2 REEP4 SAR1A SCN3B SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35C2 STOM TLCD4 TMEM143 TMEM14B TMEM35A TMEM52B VMA21 ZDHHC15 ZFYVE27
Entrez ID		9166	94101
HPRD ID		05775	15092
Ensembl ID		ENSG00000147654	ENSG00000128699
Uniprot IDs		A0A024R9E0 O00559	Q9P0S3
PDB IDs
Enriched GO Terms of Interacting Partners?
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