SYNGR1 and SPNS3

Data Source:
BioGRID (two hybrid)

		SYNGR1	SPNS3
Description		synaptogyrin 1	sphingolipid transporter 3 (putative)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Azurophil Granule Membrane Melanosome	Integral Component Of Membrane
	Molecular Function	Protein Binding	Transmembrane Transporter Activity
	Biological Process	Protein Targeting Neutrophil Degranulation Regulated Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Leukemia Inhibitory Factor	Lipid Transport Transmembrane Transport
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Cholesteryl ester levels ( 31551469) Crohn's disease ( 28067908) Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 28067908) Ovarian cancer ( 30557369) Primary biliary cholangitis ( 28425483 26394269) Primary biliary cirrhosis ( 22961000) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 28067908) vWF levels ( 30586737)	Coronary artery disease in type 1 diabetes ( 29695241) Obesity-related traits ( 23251661) Small cell lung carcinoma ( 28604730)
Interacting Genes		30 interacting genes: ADORA2A AQP6 CREB3 CREB3L1 EBP ERGIC3 FAM209A FATE1 GPR42 HAS3 LEPROT LMNA MTERF3 MYG1 NDRG4 PLEKHB2 PLIN3 PNKP RETREG3 SDCBP SLC10A6 SLC16A2 SNX1 SPG21 SPNS3 TMEM14B TMEM31 TMEM45B TMEM80 UNC93A	8 interacting genes: BTN2A2 FXYD3 LRRC25 PLP1 STATH STRIT1 SYNGR1 TMEM60
Entrez ID		9145	201305
HPRD ID		06800	14531
Ensembl ID		ENSG00000100321	ENSG00000182557
Uniprot IDs		O43759	Q6ZMD2
PDB IDs
Enriched GO Terms of Interacting Partners?
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