MTA1 and GPR183

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MTA1	GPR183
Description		metastasis associated 1	G protein-coupled receptor 183
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Microtubule NuRD Complex Intracellular Membrane-bounded Organelle	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Histone Deacetylase Binding	G Protein-coupled Receptor Activity Oxysterol Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Signal Transduction Response To Ionizing Radiation Histone Deacetylation Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Autoubiquitination	Adaptive Immune Response B Cell Activation Involved In Immune Response Mature B Cell Differentiation Involved In Immune Response Dendritic Cell Chemotaxis Immune Response Humoral Immune Response G Protein-coupled Receptor Signaling Pathway T Cell Chemotaxis Osteoclast Differentiation Leukocyte Chemotaxis Positive Regulation Of B Cell Proliferation Dendritic Cell Homeostasis T Follicular Helper Cell Differentiation Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Astrocyte Chemotaxis
Pathways		HDACs deacetylate histones SUMOylation of transcription factors ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS	Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)	Asthma ( 31959851 31619474) Inflammatory bowel disease ( 28067908 23128233) Type 1 diabetes ( 25751624)
Interacting Genes		45 interacting genes: BCL11A BLOC1S1 CCNH CSNK1G2 CYSRT1 DDX18 DYNLL1 E2F1 ERCC6 ESR1 FHL3 GPR183 GRB2 H3-4 HDAC1 HDAC2 HIF1A ITGB3BP JUN KHDRBS2 KPNA4 KRT31 KRT40 KRTAP10-8 LMO4 LRRK2 LZTS2 MAGEA11 MBD3L2 MNAT1 NACC2 NBPF19 NELFCD NOTCH2NLA PICK1 PLEKHG4 RBBP4 SAT1 SH3GL1 SH3GLB1 SUMO2 TEX11 TP53 TRIM25 UBE2I	1 interacting genes: MTA1
Entrez ID		9112	1880
HPRD ID		04633	12040
Ensembl ID		ENSG00000182979	ENSG00000169508
Uniprot IDs		Q13330 Q9BRL8	A0A024RDX2 P32249
PDB IDs		4BKX 4PBY 4PBZ 4PC0 5FXY 5ICN 6G16
Enriched GO Terms of Interacting Partners?
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