LDB2 and ISL1

  • Data Source:
  • BioGRID (two hybrid)

LDB2

ISL1

Description LIM domain binding 2 ISL LIM homeobox 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429)
  • Liver fibrosis (total hepatic collagen content) ( 32953199)
  • Number of sexual partners ( 30643258)
  • QT interval ( 23534349)
  • Rhegmatogenous retinal detachment ( 23585552)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Waist circumference ( 28552196)
  • Adult body size ( 32376654)
  • Alcohol use disorder (consumption score) ( 30940813)
  • Automobile speeding propensity ( 30643258)
  • Brain morphology (MOSTest) ( 32665545)
  • Childhood body mass index ( 33045005)
  • Childhood ear infection ( 27182965)
  • Classic bladder exstrophy ( 25763902)
  • Cortical surface area (MOSTest) ( 32665545)
  • Dental caries ( 23259602)
  • Diastolic blood pressure ( 27841878)
  • Emotional lability in attention deficit hyperactivity disorder ( 31085060)
  • General risk tolerance (MTAG) ( 30643258)
  • Heel bone mineral density ( 30598549)
  • QT interval ( 29213071)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Subcortical volume (MOSTest) ( 32665545)
  • Systolic blood pressure ( 27841878)
  • Verbal declarative memory ( 25648963)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 29 interacting genes: C14orf119 CETN3 DGCR6L EGLN3 EPM2AIP1 EXOC3L1 GGACT HDAC7 ISL1 LHX4 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LNX1 NTAQ1 PSMB1 RASIP1 RILP RLIM SDCBP SMARCD1 SSBP2 SSBP3 SSBP4 TSNAX TTC19 21 interacting genes: APP CDK6 CDKN2B CRK ESR1 HNF4A ISL2 KDM1A LDB1 LDB2 LHX1 LHX3 LMO2 LMX1A NR2F1 PECR PLCG2 RELA RLIM SMAD3 ZNF511
Entrez ID 9079 3670
HPRD ID 16022 02650
Ensembl ID ENSG00000169744 ENSG00000016082
Uniprot IDs B7Z6D0 E9PFI4 G5E9Y7 O43679 P61371
PDB IDs
Enriched GO Terms of Interacting Partners?
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