PYGO2 and TRRAP

Data Source:
BioGRID (pull down)

		PYGO2	TRRAP
Description		pygopus family PHD finger 2	transformation/transcription domain associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Beta-catenin-TCF Complex	SAGA Complex PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Chromatin Binding Protein Binding Histone Acetyltransferase Regulator Activity Histone Binding Metal Ion Binding	Transcription Coregulator Activity Protein Binding Kinase Activity
	Biological Process	Kidney Development Lens Development In Camera-type Eye Spermatid Nucleus Differentiation Brain Development Mammary Gland Development Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Histone Acetylation Positive Regulation Of Chromatin Binding Developmental Growth Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Canonical Wnt Signaling Pathway Beta-catenin-TCF Complex Assembly	DNA Repair Regulation Of Transcription, DNA-templated Phosphorylation Histone Acetylation Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Histone H2A Acetylation Beta-catenin-TCF Complex Assembly
Pathways		Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex	Formation of the beta-catenin:TCF transactivating complex Formation of the beta-catenin:TCF transactivating complex HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)	Hemoglobin levels ( 32327693) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		7 interacting genes: AKT1 BCL9 DCAF1 KAT2A NF2 SUPT3H TRRAP	18 interacting genes: ACTL6A ATXN7 AURKA BRCA1 BRD8 CDC42 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3
Entrez ID		90780	8295
HPRD ID		06065	04310
Ensembl ID		ENSG00000163348	ENSG00000196367
Uniprot IDs		Q5T170 Q9BRQ0	Q9Y4A5
PDB IDs		2XB1 4UP0 4UP5
Enriched GO Terms of Interacting Partners?
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