GADD45GIP1 and KRT34

Data Source:
BioGRID (two hybrid)

		GADD45GIP1	KRT34
Description		GADD45G interacting protein 1	keratin 34
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Ribosome	Extracellular Space Cytosol Intermediate Filament
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Viral Process Mitochondrial Translational Elongation Mitochondrial Translational Termination Mitotic Cell Cycle Arrest	Epidermis Development Keratinization Cornification
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		62 interacting genes: ANKRD28 APP AR BPIFA1 CADPS CARD10 CBY2 CCNC CEP70 CSNK2B DVL3 EAF1 ENKD1 EXOSC4 FBXO7 GADD45A GADD45B GADD45G GAS8 GEM GOLGA2 GOLGA6A GOLGA6L9 GPRASP2 HMG20A IKBKG KANK2 KIFC3 KRT27 KRT31 KRT34 KRT40 LDOC1 LRRC73 LZTS2 MAGEA11 MAGEA6 MBD3 MIPOL1 MKRN3 MRPL38 MTUS2 MYG1 MYO15B NFKBID NR4A1 NTAQ1 NUTM1 OIP5 PBX4 PICK1 PNMA1 PRDM6 PSMB1 RBM11 SPTA1 TFIP11 TRAF1 TRIM27 UPF2 WWP2 ZRANB1	253 interacting genes: A1CF ABHD15 ABI2 ADRA2C AGXT AIMP2 ALDH3B1 AMOT ANKRD11 ANKS1A ARMC7 ASMTL ATG9A ATPAF2 BATF2 BCAS2 BEX1 BEX2 BEX3 BHLHE23 BOLA3 BRME1 C11orf87 C17orf50 C1orf216 C5orf49 CBX8 CCDC120 CCDC13 CCDC146 CCDC196 CCDC198 CCDC24 CCDC28A-AS1 CCHCR1 CCNC CDC20B CDK18 CERK CFAP206 CFAP53 CHRD CHRNG CLCNKA CLDN19 CLEC18A CTRC CWC25 CYSRT1 CYTH4 DCTN3 DDIT4L DDX6 DHRS1 DMRT3 DOCK2 EFCAB3 EIF4G1 EPDR1 EXOC8 EXOSC5 FAM110A FAM214B FAM50B FAM71C FAM83A FAM90A1 FARS2 FBXW5 FNDC11 FOXD4L1 FRS3 GADD45GIP1 GAST GATAD2A GEM GLYCTK GNE GNG10 GNG13 GPS2 GRN GSC2 GSTP1 HAPLN2 HBA1 HBA2 HCK HDAC4 HGS HOXA1 HOXB5 HOXB9 HOXC8 HSPA12B HSPD1 HYAL2 ICAM4 INIP INO80B ISCU ITGB5 ITPKB JOSD1 KANK2 KCTD9 KDELR1 KIDINS220 KLC4 KLHL38 KLK8 KRT1 KRT20 KRT3 KRT6A KRT6C KRT71 KRT74 KRT75 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 KRTAP12-2 KRTAP13-1 KRTAP19-5 KRTAP19-7 KRTAP26-1 LMO2 LMO4 LRRC29 LRRC41 LYSMD1 LYVE1 MAB21L2 MAD2L2 MAP3K7CL MAPKBP1 MATR3 MBD3L2 METTL17 MIDN MIIP MKRN3 MNS1 MOS MSRB3 MYO15B MYOZ1 MYOZ3 NAB2 NAXD NEK6 NFKBID NMU NOTO NPBWR2 NUP42 P2RX7 PDE9A PDGFRB PGLYRP3 PIN1 PITX1 PITX2 PKN1 PLLP POP5 PPP1R18 PPP1R27 PPP3R2 PRPF18 PRPF31 PRR19 PRR35 PSMA1 PSMB1 PTPMT1 R3HDM2 RAB33A RAB3IL1 RASD1 RFC5 RIN1 RIPPLY1 RTP5 SAMD11 SCNM1 SEC14L4 SEMA4C SHC3 SIRPA SLC15A2 SLC22A5 SLC23A1 SLC25A42 SMARCD1 SMARCE1 SMCP SMG9 SNRPB SPAG8 SPATA46 SPRY3 STMN3 SUOX TACO1 TAPBPL TBC1D22B TCHP TEKT3 TEKT4 TENT5B TEPSIN TFAP2D THAP7 TLE5 TLX3 TMEM174 TMIE TMSB4X TRARG1 TRIM42 TRIM73 TRIML2 TSG101 TTC23 TTC9C TXLNA TXLNB USP2 UTP14C UTP23 VENTX WDR25 WWOX ZDHHC1 ZFHX3 ZFYVE26 ZIC1 ZNF124 ZNF148 ZNF319 ZNF414 ZNF446 ZNF580 ZNF581 ZNF79
Entrez ID		90480	3885
HPRD ID		05519	04137
Ensembl ID		ENSG00000179271	ENSG00000131737
Uniprot IDs		Q8TAE8	O76011
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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