ERI1 and SLBP

Data Source:
BioGRID (two hybrid)

		ERI1	SLBP
Description		exoribonuclease 1	stem-loop binding protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Histone Pre-mRNA 3'end Processing Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Histone Pre-mRNA 3'end Processing Complex Ribonucleoprotein Complex
	Molecular Function	3'-5'-exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity RRNA Binding Ribosome Binding Metal Ion Binding Histone Pre-mRNA Stem-loop Binding	RNA Binding MRNA Binding Protein Binding Identical Protein Binding Histone Pre-mRNA Stem-loop Binding Histone Pre-mRNA DCP Binding
	Biological Process	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) DNA Catabolic Process, Exonucleolytic RRNA Processing Gene Silencing By RNA RRNA 3'-end Processing Histone MRNA Catabolic Process	Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing By Stem-loop Binding And Cleavage MRNA Export From Nucleus Histone MRNA Metabolic Process MRNA Transport
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	Transport of the SLBP Dependant Mature mRNA RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Medication use (diuretics) ( 31015401) Morning person ( 30696823) Neuroticism ( 29255261) Platelet distribution width ( 32888494 27863252) Processed meat consumption ( 32066663) Red cell distribution width ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 25673412) Hip minimal joint space width ( 27701424) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		1 interacting genes: SLBP	8 interacting genes: CDK4 CDK6 DCAF11 ERI1 LSM10 PTGER4 USP8 ZNF473
Entrez ID		90459	7884
HPRD ID		11784	03884
Ensembl ID		ENSG00000104626	ENSG00000163950
Uniprot IDs		A0A024R355 Q8IV48	B3KSC5 B3KST9 B4DUW7 E7EUV9 Q14493 Q53XR2
PDB IDs		1W0H 1ZBH 1ZBU 4L8R 4QOZ	2KJM 4L8R 4QOZ
Enriched GO Terms of Interacting Partners?
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