KALRN and GFI1B

KALRN

GFI1B

Description kalirin RhoGEF kinase growth factor independent 1B transcriptional repressor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (donor effect) ( 27595289)
  • Amyotrophic lateral sclerosis ( 26580837)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682)
  • Diffuse large B-cell lymphoma or systemic lupus erythematosus ( 31407831)
  • General cognitive ability ( 29844566)
  • Hematocrit ( 32888494)
  • Heschl's gyrus morphology ( 25130324)
  • Intraocular pressure ( 29617998 29785010 31959993)
  • Longevity (age >99th survival percentile) ( 31413261)
  • Low urine pH ( 30476138)
  • Lymphocyte counts ( 32888494)
  • Marginal zone lymphoma or systemic lupus erythematosus ( 31407831)
  • Mean platelet volume ( 22139419 32888494 27863252)
  • Metabolite levels ( 23823483)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Monocyte count ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • Platelet count ( 32888494 27863252)
  • Platelet distribution width ( 32888494 27863252)
  • Plateletcrit ( 27863252)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Red cell distribution width ( 32888494)
  • Schizophrenia ( 30285260)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (1df test) ( 32227373)
  • Systolic blood pressure x dichotomous lifestyle risk score interaction (2df test) ( 32227373)
  • Thyroid peroxidase antibody levels ( 24586183)
  • Urine pH measurement ( 30476138)
Interacting Genes 16 interacting genes: ATXN7 CACNA1A CDC5L COIL DISC1 DTNBP1 ENO3 EPHB2 FASLG GFI1B LNX1 NDEL1 PAM SPTAN1 SUMO2 SUMO3 71 interacting genes: ACTN1 AGRN AJUBA ANKS3 ATXN2 BABAM2 BECN1 BEGAIN BEND5 BRCA1 CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GPAT4 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 POLR1H PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TLE5 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRF3
Entrez ID 8997 8328
HPRD ID 06859 05088
Ensembl ID ENSG00000160145 ENSG00000165702
Uniprot IDs C9IZQ6 O60229 A0A024R8F3 Q5VTD9
PDB IDs 5QQD 5QQE 5QQF 5QQG 5QQH 5QQI 5QQJ 5QQK 5QQL 5QQM 5QQN 5QU9
Enriched GO Terms of Interacting Partners?
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