CCNF and MYBL2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		CCNF	MYBL2
Description		cyclin F	MYB proto-oncogene like 2
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Centrosome Centriole Cytosol SCF Ubiquitin Ligase Complex Cell Junction	Nucleus Nucleoplasm Myb Complex
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Polyubiquitination Re-entry Into Mitotic Cell Cycle Placenta Development Negative Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Mitotic Cell Cycle Phase Transition Cell Division	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Mitotic Spindle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Polo-like kinase mediated events TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS		Height ( 28552196) Triglyceride levels ( 32203549)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: AKT1 CCNB1 CDC6 FZR1 MYBL2 RBPJ SCYL1	31 interacting genes: CCNA1 CCNA2 CCND1 CCNE1 CCNF CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN52 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBBP4 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622
Entrez ID		899	4605
HPRD ID		02574	03247
Ensembl ID		ENSG00000162063	ENSG00000101057
Uniprot IDs		P41002 Q59HD0	P10244
PDB IDs			6C48
Enriched GO Terms of Interacting Partners?
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