TRIM15 and FAM151B

Data Source:
BioGRID (two hybrid)

		TRIM15	FAM151B
Description		tripartite motif containing 15	family with sequence similarity 151 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Mesodermal Cell Fate Determination Regulation Of Gene Expression Protein Ubiquitination Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of RIG-I Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Viral Release From Host Cell
Pathways
Drugs
Diseases
GWAS		Anger ( 24489884) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Hemoglobin ( 32888494) Mean corpuscular hemoglobin ( 32888494) Neurociticism ( 29500382) Neuroticism ( 29255261) Red cell distribution width ( 32888494)	Proteinuria in chronic kidney disease ( 26420894)
Interacting Genes		39 interacting genes: ACD ACTB AXIN1 CDK6 CFL1 CORO1B CTTN EHMT1 FAM151B FAM161A FAM161B FBLIM1 FERMT2 FERMT3 GAB1 GTF2E1 IRF5 KEAP1 MED7 MSN MYBL2 NEXN PFN1 PRNP PTK2 PXN RABGEF1 ROCK1 SHC1 SNW1 SYK TAF9B TINF2 TRIM8 UBE2U VASP VCL VIM YJU2	1 interacting genes: TRIM15
Entrez ID		89870	167555
HPRD ID		15551	18272
Ensembl ID		ENSG00000204610	ENSG00000152380
Uniprot IDs		Q5SRL0 Q9C019	Q6UXP7
PDB IDs
Enriched GO Terms of Interacting Partners?
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