MBD2 and MBD3L1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MBD2	MBD3L1
Description		methyl-CpG binding domain protein 2	methyl-CpG binding domain protein 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Heterochromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex	Nucleus
	Molecular Function	Satellite DNA Binding MRNA Binding Protein Binding Methyl-CpG Binding Protein Domain Specific Binding Nucleosomal DNA Binding SiRNA Binding C2H2 Zinc Finger Domain Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RDNA Heterochromatin Assembly DNA Methylation-dependent Heterochromatin Assembly Heart Development Aging Response To Mechanical Stimulus Positive Regulation Of Wnt Signaling Pathway Response To Nutrient Levels Response To Estradiol Cellular Protein-containing Complex Assembly Positive Regulation Of Chromatin Binding Regulation Of Cell Population Proliferation Maternal Behavior ATP-dependent Chromatin Remodeling Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Embryonic Organ Development Cellular Response To Organic Cyclic Compound
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Body size at age 10 ( 32376654) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Periodontitis (Mean PAL) ( 24024966) Prostate cancer ( 29892016) Psoriasis ( 23143594)
Interacting Genes		16 interacting genes: CREBBP DHX9 GATAD2A GATAD2B GPN1 HDAC1 HDAC2 HINFP LAMTOR3 MBD3 MBD3L1 MBD3L2 PURB RBBP4 SIN3A TBP	45 interacting genes: ANKS1A BOLA2 BOLA2B C1orf109 C1orf74 CLCNKA CLIC3 CTNNA3 DTX2 EFHC1 EXOC8 FAM124B FHL2 FNDC3B FRS3 GATAD2A GPSM3 GTPBP3 IL16 KCTD9 KIFC3 LMO1 LMO3 MAD2L2 MBD2 MBD3 MLH1 MPPED2 NDUFAF3 NEK6 NXF1 SH2D4A SNAPC5 SNRPB STX11 SUOX TRAPPC2 TRAPPC2B TSGA10 TSGA10IP TSSK3 UBL5 USP20 ZNF76 ZNF77
Entrez ID		8932	85509
HPRD ID		04647	12138
Ensembl ID		ENSG00000134046	ENSG00000170948
Uniprot IDs		A0A024R2B8 Q9UBB5	Q8WWY6
PDB IDs		2L2L 6C1A 6C1T 6C1U 6C1V 6C2F 6CNP 6CNQ
Enriched GO Terms of Interacting Partners?
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