HERC2 and XPA

  • Data Source:
  • BioGRID (enzymatic study)

HERC2

XPA

Description HECT and RLD domain containing E3 ubiquitin protein ligase 2 XPA, DNA damage recognition and repair factor
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hypothyroidism ( 27182965)
  • Obesity-related traits ( 23251661)
  • Serum thyroid-stimulating hormone levels ( 24852370)
  • Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes 14 interacting genes: BDKRB2 C5AR2 CALM1 CDC42 ERG RNF11 STK11 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 UBE2N XPA 51 interacting genes: ARID3A ATM ATR AURKA BMPR1A BUB1 DDB1 DDB2 DLC1 DVL3 ERCC1 ERCC4 ERCC6 FBXW7 GPN1 GTF2E2 GTF2H1 HERC2 MEOX2 MLH1 MLH3 MSH2 MSH3 MUTYH NDEL1 NRAS PCNA PDGFRL PICK1 PMS2 POLR1C PRDM16 PRKDC PSMB1 RASSF1 RB1 RHOU RPA1 RPA2 RPA4 SKIL SMAD2 SNPH SRC STK11 TBC1D7 TRIM27 VPS26C XAB2 XPC ZNF655
Entrez ID 8924 7507
HPRD ID 06905 02045
Ensembl ID ENSG00000128731 ENSG00000136936
Uniprot IDs A8KAQ8 O95714 P23025
PDB IDs 2KEO 3KCI 4L1M 6WW3 6WW4 1D4U 1XPA 2JNW 6J44 6LAE 6RO4
Enriched GO Terms of Interacting Partners?
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