NRP1 and CACNB2

  • Data Source:
  • BioGRID (two hybrid)

NRP1

CACNB2

Description neuropilin 1 calcium voltage-gated channel auxiliary subunit beta 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Antisaccade task score ( 31596458)
  • Apolipoprotein B levels ( 32203549)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood pressure ( 21909110)
  • Body mass index ( 28892062)
  • Brain volume in infants (grey matter) ( 28763065)
  • Cadmium levels ( 26025379)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diastolic blood pressure ( 19430479 27841878 21909115 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diverticular disease ( 30177863)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Hypertension ( 31879980 19430479 21909115)
  • LDL cholesterol levels ( 32203549)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328)
  • Primary tooth development (time to first tooth eruption) ( 23704328)
  • Protein quantitative trait loci ( 18464913)
  • Pulse pressure ( 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Quantitative traits ( 19197348)
  • Response to antiepileptic drugs in genetic generalized epilepsy ( 32308125)
  • Schizophrenia ( 28991256 25056061 29483656 30285260 23974872)
  • Small vessel stroke ( 26732560)
  • Systolic blood pressure ( 28135244 19430479 27841878 21909115 28739976 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 23 interacting genes: FGF1 FGF2 FGF4 FGF7 FGFR1 FLT1 GIPC1 KDR L1CAM NRP2 PGF PLXNA1 PLXNB1 RPL27 SEMA3A SEMA3B SEMA3C SEMA3F TGFBR1 TGFBR2 TGFBR3 VEGFA VEGFB 6 interacting genes: CTBP2 HEXIM2 PRKACA PRMT5 REM1 TMEM174
Entrez ID 8829 783
HPRD ID 03642 02473
Ensembl ID ENSG00000099250 ENSG00000165995
Uniprot IDs A8K9V7 O14786 Q59F20 Q68DN3 Q6AWA9 Q6X907 A0A494C0B2 A0A494C184 Q08289 Q59H42 Q5VVH1
PDB IDs 1KEX 2QQI 2QQM 2QQN 3I97 4DEQ 4RN5 5C7G 5IJR 5IYY 5J1X 5JGI 5JGQ 5JHK 5L73 6FMC 6FMF 7JJC
Enriched GO Terms of Interacting Partners?
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