CACNB2 and CTBP2

  • Data Source:
  • BioGRID (two hybrid)

CACNB2

CTBP2

Description calcium voltage-gated channel auxiliary subunit beta 2 C-terminal binding protein 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Antisaccade task score ( 31596458)
  • Apolipoprotein B levels ( 32203549)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blood pressure ( 21909110)
  • Body mass index ( 28892062)
  • Brain volume in infants (grey matter) ( 28763065)
  • Cadmium levels ( 26025379)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Diastolic blood pressure ( 19430479 27841878 21909115 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diverticular disease ( 30177863)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Hypertension ( 31879980 19430479 21909115)
  • LDL cholesterol levels ( 32203549)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Metabolite levels (HVA/MHPG ratio) ( 23319000)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity-related traits ( 23251661)
  • Primary tooth development (number of teeth) ( 23704328)
  • Primary tooth development (time to first tooth eruption) ( 23704328)
  • Protein quantitative trait loci ( 18464913)
  • Pulse pressure ( 30578418)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Quantitative traits ( 19197348)
  • Response to antiepileptic drugs in genetic generalized epilepsy ( 32308125)
  • Schizophrenia ( 28991256 25056061 29483656 30285260 23974872)
  • Small vessel stroke ( 26732560)
  • Systolic blood pressure ( 28135244 19430479 27841878 21909115 28739976 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes 6 interacting genes: CTBP2 HEXIM2 PRKACA PRMT5 REM1 TMEM174 99 interacting genes: ACTG1 AKTIP APP BAZ2B BCAS3 BCL3 C15orf39 CACNB1 CACNB2 CACNB3 CACNB4 CAPN7 CASP8AP2 CATSPER1 CBX4 CCDC120 CCNH CCR5 CDKN2A CEP68 CSTF2 CTBP1 CTPS2 DMRTB1 DTNB DUSP21 DVL2 EEF1D EGLN3 EIF4G1 ELAC2 ENKD1 EP300 FHL3 FLI1 FOXP2 FUNDC1 GLIS2 H3-4 HEMGN HIC1 HOXA5 HOXB5 HOXC5 IKZF1 IKZF2 KCNIP3 KLF3 KLF8 KYNU LCORL LMO4 MDM2 MECOM MSRB3 NEK6 NOL4 NOL4L NRIP1 PLCB1 PNN PPP1R15A PROX1 PSMF1 QARS1 RAI2 RBBP8NL RIMBP3 RNF135 RPL17 RPL7A RPS28 RPS29 RPS4X SDCBP SHISA6 SOX13 SOX6 STUB1 STX11 TEAD3 TGIF1 TLE5 TRIML2 TSHZ3 UBC UBE2I VRTN XRCC6 ZBP1 ZBTB18 ZBTB42 ZEB1 ZEB2 ZFPM1 ZFPM2 ZNF512B ZNF750 ZSCAN4
Entrez ID 783 1488
HPRD ID 02473 04016
Ensembl ID ENSG00000165995 ENSG00000175029
Uniprot IDs A0A494C0B2 A0A494C184 Q08289 Q59H42 Q5VVH1 P56545
PDB IDs 2OME 4LCJ
Enriched GO Terms of Interacting Partners?
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