KRT36 and CCBE1

Data Source:
BioGRID (two hybrid)

		KRT36	CCBE1
Description		keratin 36	collagen and calcium binding EGF domains 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Extracellular Exosome	Collagen Trimer Extracellular Space Extracellular Matrix
	Molecular Function	Structural Constituent Of Skin Epidermis	Protease Binding Calcium Ion Binding Protein Binding Collagen Binding
	Biological Process	Biological_process Keratinization Regulation Of Keratinocyte Differentiation Cornification	Lymphangiogenesis Sprouting Angiogenesis Respiratory System Process Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Processing Lung Development Positive Regulation Of Angiogenesis Venous Blood Vessel Morphogenesis Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Lymphangiogenesis
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Age-related hearing impairment ( 24939585) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23857890) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) PR interval ( 32439900) Pre-treatment viral load in HIV-1 infection ( 31219150) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		52 interacting genes: ABI2 ABI3 AIMP2 AMOT APP BCAS2 C1orf216 CCBE1 CCHCR1 CDC23 DMRT3 EXOC8 GEM GPS2 HCK HGS HOXC8 KRT1 KRT2 KRT3 KRT4 KRT6A KRT6C KRT73 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT85 KRT86 MAP3K1 MYOZ1 MYOZ3 PKN1 PLEKHN1 PPP1R18 PSMB1 QARS1 RESF1 RIBC1 SMURF1 TMSB4X TRAF4 TSGA10IP TTC23 TTLL10 TXLNA ZNF414 ZNF785	11 interacting genes: CEP55 COPS6 FBXO7 INCA1 KLHL12 KRT27 KRT36 LNX1 SIAH2 STX11 TOX4
Entrez ID		8689	147372
HPRD ID		05174	08703
Ensembl ID		ENSG00000126337	ENSG00000183287
Uniprot IDs		O76013	Q6UXH8
PDB IDs
Enriched GO Terms of Interacting Partners?
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