MARCO and SCGB3A1

Data Source:
HPRD (in vivo)

		MARCO	SCGB3A1
Description		macrophage receptor with collagenous structure	secretoglobin family 3A member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Collagen Trimer Intracellular Anatomical Structure Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Membrane	Extracellular Space Extracellular Exosome
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Cargo Receptor Activity Pattern Recognition Receptor Activity	Cytokine Activity Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Endocytosis Receptor-mediated Endocytosis Phagocytosis, Engulfment Cell Surface Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Apoptotic Cell Clearance Innate Immune Response Positive Regulation Of ERK1 And ERK2 Cascade Amyloid-beta Clearance	Signal Transduction Negative Regulation Of Cell Growth Regulation Of Cell Population Proliferation Positive Regulation Of Myoblast Fusion
Pathways		Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs		Titanium dioxide Silicon dioxide
Diseases
GWAS		Lung function (FVC) ( 30061609) Medication use (adrenergics, inhalants) ( 31015401) Triglyceride levels ( 32203549)	Blood protein levels ( 30072576) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		2 interacting genes: SCGB3A1 SCGB3A2	10 interacting genes: AURKA BAG4 FBXW7 FGFR4 MARCO NOTCH3 RHBDD2 TGFB1 TSG101 XRCC3
Entrez ID		8685	92304
HPRD ID		05337	05932
Ensembl ID		ENSG00000019169	ENSG00000161055
Uniprot IDs		Q4ZG40 Q9UEW3	Q96QR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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