CHRD and TWSG1

Data Source:
HPRD (in vitro)

		CHRD	TWSG1
Description		chordin	twisted gastrulation BMP signaling modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Cytokine Binding	Protein Binding Transforming Growth Factor Beta Binding
	Biological Process	Skeletal System Development Positive Regulation Of Mesenchymal Cell Proliferation BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Negative Regulation Of Cell Migration Negative Regulation Of BMP Signaling Pathway Floor Plate Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Cell Adhesion	Ossification Mesoderm Formation Negative Regulation Of Cytokine Production Transforming Growth Factor Beta Receptor Signaling Pathway Salivary Gland Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Hemopoiesis Cell Differentiation BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Platelet count ( 32888494 20139978) Plateletcrit ( 32888494 27863252)	Dental caries ( 23064961)
Interacting Genes		57 interacting genes: ADAMTSL4 ATN1 BMP1 BMP2 CATSPER1 CD36 CHRDL2 CYSRT1 F2R GATA1 HOXA1 HRG INCA1 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP19-2 KRTAP19-5 KRTAP22-1 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 LCE1C LCE1F LCE5A LIN7A MEOX2 NBPF19 NOTCH2NLA NR0B2 NR4A3 OTX1 PLSCR1 POU4F2 RGS17 SLC15A2 SMAD3 SPRY1 SPRY2 SPRY3 TLL1 TRIM42 TSPAN4 TWSG1	10 interacting genes: BMP1 BMP4 CHRD FAM209A FNDC9 GJA8 GPRC5D LRRC4C SGTA TNS2
Entrez ID		8646	57045
HPRD ID		04592	05443
Ensembl ID		ENSG00000090539	ENSG00000128791
Uniprot IDs		E7ESX1 Q8N2W7 Q9H2X0	Q9GZX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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