RGS20 and NEK8

Data Source:
BioGRID (two hybrid)

		RGS20	NEK8
Description		regulator of G protein signaling 20	NIMA related kinase 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane	Nucleus Cytoplasm Centrosome Cilium Ciliary Inversin Compartment Ciliary Base
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Protein Phosphorylation Chromosome Segregation Determination Of Left/right Symmetry Heart Development Animal Organ Morphogenesis Regulation Of Hippo Signaling
Pathways		G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Chronic obstructive pulmonary disease ( 32222710) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)	Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		54 interacting genes: ABHD17A ADRB2 ALPP AQP1 CATSPER1 COL8A1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HRG HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP5-9 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAPKBP1 NECTIN2 NECTIN3 NEK8 NUFIP2 OSTM1 OTX1 PTGER3 PTPMT1 RANBP3 STMN2 TBC1D16 VASN	11 interacting genes: ACVR1 ADAMTSL4 KRTAP13-2 NEK9 OXER1 RGS20 TCF4 TGFBR1 TRIM42 TRIM69 UBC
Entrez ID		8601	284086
HPRD ID		06225	14822
Ensembl ID		ENSG00000147509	ENSG00000160602
Uniprot IDs		B3KSW4 H9NIM5 O76081	Q86SG6
PDB IDs
Enriched GO Terms of Interacting Partners?
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