PRPF18 and ZNF526

Data Source:
BioGRID (two hybrid)

		PRPF18	ZNF526
Description		pre-mRNA processing factor 18	zinc finger protein 526
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex U5 SnRNP Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Post-spliceosomal Complex	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA Processing RNA Splicing Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) ( 24025145) Craniofacial microsomia ( 26853712) Lupus nephritis in systemic lupus erythematosus ( 24925725) Post bronchodilator FEV1/FVC ratio ( 26634245) Skin pigmentation ( 28300201)	Meat-related diet ( 32066663)
Interacting Genes		81 interacting genes: AGTRAP AMOTL2 AP2M1 ASCC2 BEGAIN BICD2 BLZF1 CADPS CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC150 CCDC57 CCNC CDR2 CEP70 CSRNP1 DVL3 EFHC2 EVI5L FERMT3 FSD2 GAS8 GCC1 GOLGA2 GOLGA6L9 GPBP1 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKBKG IKZF1 KANK2 KCTD7 KIFC3 KRT31 KRT34 KRT35 KRT39 KRT40 LDOC1 LZTS1 LZTS2 MCC MDFI MEOX2 MTUS2 NACC1 NECAB2 NINL NUTM1 NUTM2F OSBPL3 PDE9A PFDN5 PIBF1 PICK1 PLEKHG4 PNMA1 PPIH PRKAR1B RHOU RINT1 SCHIP1 SPRED1 STX11 TRAF2 TRIM23 TRIM27 TRIM54 TSNAX TSNAXIP1 UBXN11 ZNF526 ZNF639 ZRANB1	54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837
Entrez ID		8559	116115
HPRD ID		05407	15818
Ensembl ID		ENSG00000165630	ENSG00000167625
Uniprot IDs		Q99633	H9ZYJ3 Q8TF50
PDB IDs		2DK4
Enriched GO Terms of Interacting Partners?
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