MAPKAPK5 and LSR

Data Source:
BioGRID (two hybrid)

		MAPKAPK5	LSR
Description		MAPK activated protein kinase 5	lipolysis stimulated lipoprotein receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Plasma Membrane Integral Component Of Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Chylomicron Tricellular Tight Junction Extracellular Exosome
	Molecular Function	P53 Binding Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity MAP Kinase Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Mitogen-activated Protein Kinase Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	MAPK Cascade Activation Of MAPK Activity Regulation Of Translation Signal Transduction Ras Protein Signal Transduction Peptidyl-serine Phosphorylation Negative Regulation Of TOR Signaling Positive Regulation Of Telomere Maintenance Via Telomerase Intracellular Signal Transduction Protein Autophosphorylation Positive Regulation Of Telomerase Activity Stress-induced Premature Senescence Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Telomere Capping	Liver Development Regulation Of Lipid Metabolic Process Maintenance Of Blood-brain Barrier Establishment Of Blood-brain Barrier Establishment Of Skin Barrier Protein Localization To Tricellular Tight Junction Tricellular Tight Junction Assembly
Pathways		Oxidative Stress Induced Senescence MAPK6/MAPK4 signaling Regulation of TP53 Activity through Phosphorylation	LDL clearance VLDL clearance
Drugs		Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 26426971) Coffee consumption ( 29367735) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mean spheric corpuscular volume ( 32888494) Psoriasis ( 28537254)	Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) Red blood cell count ( 27863252)
Interacting Genes		29 interacting genes: ATF2 CDCA8 EEF2K EIF4E EIF4EBP1 GYS1 HSPB1 HSPB2 JUN LSR MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK4 MAPK6 MAPK9 MBP MYH11 PARK7 PLA2G4A RPL13 SRPK1 SRPK2 TAB1 TP53 ZNF282 ZNF576	3 interacting genes: MAPKAPK5 RARG YWHAG
Entrez ID		8550	51599
HPRD ID		09467	17283
Ensembl ID		ENSG00000089022	ENSG00000105699
Uniprot IDs		Q8IW41	Q86X29
PDB IDs
Enriched GO Terms of Interacting Partners?
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