DOCK7 and PRNP

  • Data Source:
  • BioGRID (two hybrid)

DOCK7

PRNP

Description dedicator of cytokinesis 7 prion protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Cholesterol, total ( 28270201 19060911 25961943 20686565)
  • Crohn's disease ( 28067908)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels ( 32203549)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol ( 19060911 30275531 25961943 20686565)
  • LDL cholesterol levels ( 32203549 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lipid traits ( 24386095)
  • Low density lipoprotein cholesterol levels ( 32154731)
  • Mean platelet volume ( 32888494)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels ( 23823483 22916037)
  • Metabolite levels (lipid measures) ( 27005778)
  • Platelet distribution width ( 32888494 27863252)
  • Pneumococcal bacteremia ( 27236921)
  • Regular attendance at a gym or sports club ( 29970889)
  • Serum metabolite levels ( 31636271)
  • Serum metabolite levels (CMS) ( 31636271)
  • Total cholesterol levels ( 29403010 30275531)
  • Triglyceride levels ( 32154731 31170924 29403010 29615537 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 18193044 20864672 19060911 25961943 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
  • Creutzfeldt-Jakob disease ( 19081515)
  • Creutzfeldt-Jakob disease (sporadic) ( 32949544 25918841)
  • Creutzfeldt-Jakob disease (variant) ( 22137330)
  • KANNO antigen negativity ( 31020675)
  • Platelet aggregation ( 20526338)
  • Prion diseases ( 22210626)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 18 interacting genes: ANXA7 BCL2L1 CDC42 CDKN1A GRB7 NOD2 NSD3 PPP2CB PRNP RAC1 RHOA RPP14 SMN1 SNCA TK1 TRIM55 TRIM63 YWHAG 96 interacting genes: ABT1 ADAM23 ADAP2 ADRB2 AGO1 AIFM3 APBB1 APLP1 APLP2 APOE ARHGAP15 ATIC BAG6 BAZ2B C7orf50 CAV1 CCDC149 CCR1 CIRBP CLSTN1 CLU CNP CNTN1 CRYAB CSN3 CSNK2A1 CSNK2A2 CSNK2B CWC15 DDX47 DNM1 DOCK7 DPP6 DYRK3 ERI3 F2RL1 FAM27E3 FBLN5 FBXO45 FGF13 FHL1 FZD7 GRB2 HAX1 HSPA5 HSPD1 IER3 KIAA1191 KIFAP3 L1CAM LMNA LSAMP MAG MARK4 MMADHC MOG MTG1 NCAM1 NCAM2 NECTIN1 NHP2 NIPSNAP2 NOB1 OPCML P4HB PDE4DIP PLG PPFIBP2 PPP1R14A PSMA3 PSMB5 PTAFR PTRH1 PYM1 RBM22 RNPC3 RPL41 SCNM1 SEC31A SPARCL1 STARD5 STIP1 SURF2 TBPL1 TMEM237 TRIM15 TSC22D4 TSLP TYMSOS UTP4 WDR5 WDR61 ZFYVE28 ZKSCAN8 ZNF408 ZNF740
Entrez ID 85440 5621
HPRD ID 16833 01453
Ensembl ID ENSG00000116641 ENSG00000171867
Uniprot IDs Q96N67 F7VJQ1 P04156 Q53YK7
PDB IDs 6AJ4 6AJL 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1OEH 1OEI 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 2IV4 2IV5 2IV6 2K1D 2KUN 2LBG 2LEJ 2LFT 2LSB 2LV1 2M8T 2OL9 2W9E 3HAF 3HAK 3HEQ 3HER 3HES 3HJ5 3HJX 3MD4 3MD5 3NHC 3NHD 3NVF 4DGI 4E1H 4E1I 4KML 4N9O 5L6R 5YJ4 5YJ5 6DU9 6LNI 6PQ5 6PQA 6SUZ 6SV2 6UUR
Enriched GO Terms of Interacting Partners?
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