PPFIA3 and PPFIA2

Data Source:
HPRD (in vitro)

		PPFIA3	PPFIA2
Description		PTPRF interacting protein alpha 3	PTPRF interacting protein alpha 2
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Presynaptic Active Zone Presynaptic Active Zone Cytoplasmic Component Epididymosome Glutamatergic Synapse	Cytoplasm Cytosol Cell Surface Axon Dendritic Spine Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Presynapse
	Biological Process	Neurotransmitter Secretion Glutamate Secretion Synaptic Vesicle Docking Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization	Cell-matrix Adhesion Neurotransmitter Secretion Glutamate Secretion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Exocytosis
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Adult body size ( 32376654) Leukoderma in response to rhododendrol ( 32558222)	Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)
Interacting Genes		16 interacting genes: CAST CBY2 DISC1 ERC2 GIT1 PPFIA1 PPFIA2 PPFIBP1 PPFIBP2 PPP1R13B PTPRD PTPRF PTPRS PTPRU SORBS3 TFIP11	13 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS
Entrez ID		8541	8499
HPRD ID		04393	04392
Ensembl ID		ENSG00000177380	ENSG00000139220
Uniprot IDs		O75145	B7Z7Y5 G3V200 H0YHK3 O75334 Q4LE62
PDB IDs			3TAC 3TAD 6IUH
Enriched GO Terms of Interacting Partners?
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